Culture of type II pneumocytes on a type II cell-derived fibronectin-rich matrix.
@article{Rannels1987CultureOT, title={Culture of type II pneumocytes on a type II cell-derived fibronectin-rich matrix.}, author={S. Rannels and C. Fisher and L. Heuser and D. Rannels}, journal={The American journal of physiology}, year={1987}, volume={253 6 Pt 1}, pages={ C759-65 } }
Recent evidence suggests that during primary culture, type II pneumocytes synthesize and deposit components of an extracellular matrix. The present study investigated the response of freshly isolated type II cells to a preformed, fibronectin-rich matrix synthesized by type II cells over a 6-day interval of primary culture on a plastic surface. Type II cells on 6-day matrix (M6) degraded the preformed matrix and deposited newly synthesized fibronectin more rapidly than cells on plastic… CONTINUE READING
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