Culture-independent genome sequencing of clinical samples reveals an unexpected heterogeneity of infections by Chlamydia pecorum.

@article{Bachmann2015CultureindependentGS,
  title={Culture-independent genome sequencing of clinical samples reveals an unexpected heterogeneity of infections by Chlamydia pecorum.},
  author={Nathan L. Bachmann and Mitchell J. Sullivan and Martina Jelocnik and Garry S. A. Myers and Peter Timms and Adam Polkinghorne},
  journal={Journal of clinical microbiology},
  year={2015},
  volume={53 5},
  pages={
          1573-81
        }
}
Chlamydia pecorum is an important global pathogen of livestock, and it is also a significant threat to the long-term survival of Australia's koala populations. This study employed a culture-independent DNA capture approach to sequence C. pecorum genomes directly from clinical swab samples collected from koalas with chlamydial disease as well as from sheep with arthritis and conjunctivitis. Investigations into single-nucleotide polymorphisms within each of the swab samples revealed that a… CONTINUE READING

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