Culture-independent approaches to chlamydial genomics

@inproceedings{TaylorBrown2018CultureindependentAT,
  title={Culture-independent approaches to chlamydial genomics},
  author={Alyce Taylor-Brown and Danielle Madden and Adam Polkinghorne},
  booktitle={Microbial genomics},
  year={2018}
}
The expanding field of bacterial genomics has revolutionized our understanding of microbial diversity, biology and phylogeny. For most species, DNA extracted from culture material is used as the template for genome sequencing; however, the majority of microbes are actually uncultivable, and others, such as obligate intracellular bacteria, require laborious tissue culture to yield sufficient genomic material for sequencing. Chlamydiae are one such group of obligate intracellular microbes whose… CONTINUE READING
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