Culture and properties of cells derived from Kaposi sarcoma.

  title={Culture and properties of cells derived from Kaposi sarcoma.},
  author={Jacqueline A Corbeil and L. A. R. Evans and E. Z. Vasak and David A. Cooper and Ronald Penny},
  journal={Journal of immunology},
  volume={146 9},
We describe the establishment of four continuous cell cultures isolated from pleural or peritoneal fluid of patients with Kaposi sarcoma (KS) and show evidence that these cells are derived from vascular endothelium. Although provision of an extracellular matrix (fibronectin, laminin, or matrigel) was essential, the cell cultures were not dependent on exogenously added growth factors (platelet-derived growth factor, epidermal growth factor with or without heparin) for continuous culture… CONTINUE READING


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