Cultivation-based multiplex phenotyping of human gut microbiota allows targeted recovery of previously uncultured bacteria.

@article{Rettedal2014CultivationbasedMP,
  title={Cultivation-based multiplex phenotyping of human gut microbiota allows targeted recovery of previously uncultured bacteria.},
  author={Elizabeth A. Rettedal and Heidi K. Gumpert and Morten Otto Alexander Sommer},
  journal={Nature communications},
  year={2014},
  volume={5},
  pages={
          4714
        }
}
The human gut microbiota is linked to a variety of human health issues and implicated in antibiotic resistance gene dissemination. Most of these associations rely on culture-independent methods, since it is commonly believed that gut microbiota cannot be easily or sufficiently cultured. Here, we show that carefully designed conditions enable cultivation of a representative proportion of human gut bacteria, enabling rapid multiplex phenotypic profiling. We use this approach to determine the… CONTINUE READING
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