Culprit or correlate? An application of the Bradford Hill criteria to Vitamin E acetate

@article{Feldman2020CulpritOC,
  title={Culprit or correlate? An application of the Bradford Hill criteria to Vitamin E acetate},
  author={R. Feldman and J. Meiman and M. Stanton and D. Gummin},
  journal={Archives of Toxicology},
  year={2020},
  volume={94},
  pages={2249-2254}
}
Vitamin E acetate (VEA) has come under significant scrutiny due to its association with e-cigarette, or vaping, product use-associated lung injury (EVALI). In 1965, Sir Austin Bradford Hill proposed a set of criteria used to critically assess an association for causality. In this article, we apply the Bradford Hill causation criteria to VEA and the EVALI outbreak to clarify what further areas of study are needed to strengthen the causal argument. Additionally, we highlight the need for… Expand
2 Citations

References

SHOWING 1-10 OF 40 REFERENCES
Vitamin E Acetate in Bronchoalveolar-Lavage Fluid Associated with EVALI.
Potential for release of pulmonary toxic ketene from vaping pyrolysis of vitamin E acetate
  • D. Wu, D. O'Shea
  • Chemistry, Medicine
  • Proceedings of the National Academy of Sciences
  • 2020
Two faces of vitamin E in the lung.
Hydrocarbon toxicity: A review
Respiratory failure caused by lipoid pneumonia from vaping e-cigarettes
An Animal Model of Inhaled Vitamin E Acetate and EVALI-like Lung Injury.
...
1
2
3
4
...