Cues and regulatory pathways involved in natural competence and transformation in pathogenic and environmental Gram-negative bacteria.

@article{Seitz2013CuesAR,
  title={Cues and regulatory pathways involved in natural competence and transformation in pathogenic and environmental Gram-negative bacteria.},
  author={Patrick Seitz and Melanie Blokesch},
  journal={FEMS microbiology reviews},
  year={2013},
  volume={37 3},
  pages={336-63}
}
Bacterial genomics is flourishing, as whole-genome sequencing has become affordable, readily available and rapid. As a result, it has become clear how frequently horizontal gene transfer (HGT) occurs in bacteria. The potential implications are highly significant because HGT contributes to several processes, including the spread of antibiotic-resistance cassettes, the distribution of toxin-encoding phages and the transfer of pathogenicity islands. Three modes of HGT are recognized in bacteria… CONTINUE READING

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