Cucurbitacin B induces differentiation, cell cycle arrest, and actin cytoskeletal alterations in myeloid leukemia cells.

Abstract

Cucurbitacins have long been utilized for their abortifacient and anti-inflammatory effects; however, little is known about their mechanism of action. In this study, we have demonstrated robust antiproliferative effects of CuB on various leukemia and lymphoma cell lines, as well as on primary mononuclear bone marrow cells derived from patients with acute… (More)
DOI: 10.1016/j.leukres.2008.01.019

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Cite this paper

@article{Haritunians2008CucurbitacinBI, title={Cucurbitacin B induces differentiation, cell cycle arrest, and actin cytoskeletal alterations in myeloid leukemia cells.}, author={Talin Haritunians and Saskia Gueller and Ling Zhang and Riem E Badr and Dong Yin and Hongtao Xing and Ming Fung and H Phillip Koeffler}, journal={Leukemia research}, year={2008}, volume={32 9}, pages={1366-73} }