Cuckoo search epistasis: a new method for exploring significant genetic interactions

  title={Cuckoo search epistasis: a new method for exploring significant genetic interactions},
  author={Mehran Aflakparast and Hadi Salimi and Alireza Gerami and M-P Dub{\'e} and Shyam Visweswaran and Ali Masoudi-Nejad},
The advent of high-throughput sequencing technology has resulted in the ability to measure millions of single-nucleotide polymorphisms (SNPs) from thousands of individuals. Although these high-dimensional data have paved the way for better understanding of the genetic architecture of common diseases, they have also given rise to challenges in developing computational methods for learning epistatic relationships among genetic markers. We propose a new method, named cuckoo search epistasis (CSE… CONTINUE READING
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