Cu-Catalyzed Stereoselective γ-Alkylation of Enones.

Abstract

A general regio- and stereoselective γ-C-C bond formation is achieved using α-halocarbonyl compounds and dienol ethers via Cu(II) catalysis. This method constitutes a novel approach to the challenging 1,6-dioxygenation motif. A range of γ-substituted enones, including many bearing all-carbon quaternary centers, are available through a simple protocol under… (More)
DOI: 10.1021/jacs.6b02565

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Cite this paper

@article{Chen2016CuCatalyzedS, title={Cu-Catalyzed Stereoselective γ-Alkylation of Enones.}, author={Xiaohong Chen and Xiaoguang Liu and Justin T Mohr}, journal={Journal of the American Chemical Society}, year={2016}, volume={138 20}, pages={6364-7} }