Crystalloids versus colloids: exploring differences in fluid requirements by systematic review and meta-regression.

@article{Corts2015CrystalloidsVC,
  title={Crystalloids versus colloids: exploring differences in fluid requirements by systematic review and meta-regression.},
  author={Diego Orbegozo Cort{\'e}s and Teresa Gamarano Barros and Hassane Njimi and J K Vincent},
  journal={Anesthesia and analgesia},
  year={2015},
  volume={120 2},
  pages={389-402}
}
BACKGROUND Positive fluid balance has been associated with worse outcomes, and knowledge of differences in the amounts of different types of fluid needed to achieve the same end points may have important clinical implications. Large molecules persist longer in the blood vessels than smaller molecules, such that less IV colloid may be needed to achieve similar hemodynamic end points compared with crystalloid. Recent clinical data have, however, challenged this physiological concept, with… CONTINUE READING
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