Crystallographic characterization of geometry and conformation of TOAC, a nitroxide spin-labelled C alpha,alpha-disubstituted glycine, in simple derivatives and model peptides.

Abstract

The molecular and crystal structures of one derivative and two oligopeptides of TOAC, a nitroxide spin-labelled C alpha, alpha-disubstituted glycine, have been determined by X-ray diffraction. The derivative is the 5(4H)-oxazolone from Piv-TOAC-OH; the oligopeptides are Z-TOAC-(L-Ala)2-NHtBu sesquihydrate and pBrBz-TOAC-(L-Ala)2-TOAC-L-Ala-NHtBu hemihydrate… (More)

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@article{FlippenAnderson1996CrystallographicCO, title={Crystallographic characterization of geometry and conformation of TOAC, a nitroxide spin-labelled C alpha,alpha-disubstituted glycine, in simple derivatives and model peptides.}, author={Judith L. Flippen-Anderson and Clifford George and Giada Valle and Em{\'i}lia Valente and Armandodoriano Bianco and Fernando Formaggio and Marco Crisma and Claudio Toniolo}, journal={International journal of peptide and protein research}, year={1996}, volume={47 4}, pages={231-8} }