Crystallographic analysis of small ribozymes and riboswitches.

  title={Crystallographic analysis of small ribozymes and riboswitches.},
  author={Geoffrey M Lippa and Joseph A. Liberman and Jermaine L. Jenkins and Jolanta Krucinska and Mohammad Salim and Joseph E Wedekind},
  journal={Methods in molecular biology},
Ribozymes and riboswitches are RNA motifs that accelerate biological reactions and regulate gene expression in response to metabolite recognition, respectively. These RNA molecules gain functionality via complex folding that cannot be predicted a priori, and thus requires high-resolution three-dimensional structure determination to locate key functional… CONTINUE READING