Crystallization of ovine placental lactogen in a 1:2 complex with the extracellular domain of the rat prolactin receptor.

@article{Christinger1998CrystallizationOO,
  title={Crystallization of ovine placental lactogen in a 1:2 complex with the extracellular domain of the rat prolactin receptor.},
  author={Hans W. Christinger and Patricia A. Elkins and Yael Sandowski and Edna Sakal and Arieh Gertler and A. Kossiakoff and Abraham M de Vos},
  journal={Acta crystallographica. Section D, Biological crystallography},
  year={1998},
  volume={54 Pt 6 Pt 2},
  pages={1408-11}
}
Growth hormone and prolactin control somato-lactogenic biology. While high-resolution crystal structures have been determined for receptor complexes of human growth hormone, no such information exists for prolactin. A stable 1:2 complex was formed between ovine placental lactogen, a close prolactin homologue, and two copies of the extracellular portion of… CONTINUE READING