Crystallization and preliminary structural characterization of the two actin isoforms of the malaria parasite.

Abstract

Malaria is a devastating disease caused by apicomplexan parasites of the genus Plasmodium that use a divergent actin-powered molecular motor for motility and invasion. Plasmodium actin differs from canonical actins in sequence, structure and function. Here, the purification, crystallization and secondary-structure analysis of the two Plasmodium actin… (More)
DOI: 10.1107/S174430911302441X

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