Crystallization and preliminary X-ray crystallographic studies of the coiled-coil domain of PIST.


PIST [PDZ (PSD-95, Discs-large and ZO-1) protein interacting specifically with TC10] functions as a regulator of membrane trafficking with Rab6A. Recently, the involvement of the fusion of PIST with ROS1 in cancer development has been identified. In this study, the coiled-coil domain of PIST, which is the domain responsible for interaction with Rab6A and… (More)
DOI: 10.1107/S1744309113007082