Crystalline solids.

@article{Vippagunta2001CrystallineS,
  title={Crystalline solids.},
  author={Sudha R. Vippagunta and Harry G. Brittain and David J. W. Grant},
  journal={Advanced drug delivery reviews},
  year={2001},
  volume={48 1},
  pages={3-26}
}
Many drugs exist in the crystalline solid state due to reasons of stability and ease of handling during the various stages of drug development. Crystalline solids can exist in the form of polymorphs, solvates or hydrates. Phase transitions such as polymorph interconversion, desolvation of solvate, formation of hydrate and conversion of crystalline to amorphous form may occur during various pharmaceutical processes, which may alter the dissolution rate and transport characteristics of the drug… CONTINUE READING

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