Crystal structures of two viral peptides in complex with murine MHC class I H-2Kb.

@article{Fremont1992CrystalSO,
  title={Crystal structures of two viral peptides in complex with murine MHC class I H-2Kb.},
  author={Daved H. Fremont and M. Matsumura and Enrico A. Stura and Per A. Peterson and Ian A. Wilson},
  journal={Science},
  year={1992},
  volume={257 5072},
  pages={
          919-27
        }
}
The x-ray structures of a murine MHC class I molecule (H-2Kb) were determined in complex with two different viral peptides, derived from the vesicular stomatitis virus nucleoprotein (52-59), VSV-8, and the Sendai virus nucleoprotein (324-332), SEV-9. The H-2Kb complexes were refined at 2.3 A for VSV-8 and 2.5 A for SEV-9. The structure of H-2Kb exhibits a high degree of similarity with human HLA class I, although the individual domains can have slightly altered dispositions. Both peptides bind… 
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