Crystal structures of the antitermination factor NusB from Thermotoga maritima and implications for RNA binding.

@article{Bonin2004CrystalSO,
  title={Crystal structures of the antitermination factor NusB from Thermotoga maritima and implications for RNA binding.},
  author={I. Bonin and Rudolf Robelek and H. Benecke and H. Urlaub and A. Bacher and G. Richter and M. Wahl},
  journal={The Biochemical journal},
  year={2004},
  volume={383 Pt. 3},
  pages={
          419-28
        }
}
  • I. Bonin, Rudolf Robelek, +4 authors M. Wahl
  • Published 2004
  • Biology, Medicine
  • The Biochemical journal
  • NusB is a prokaryotic transcription factor involved in antitermination processes, during which it interacts with the boxA portion of the mRNA nut site. Previous studies have shown that NusB exhibits an all-helical fold, and that the protein from Escherichia coli forms monomers, while Mycobacterium tuberculosis NusB is a dimer. The functional significance of NusB dimerization is unknown. We have determined five crystal structures of NusB from Thermotoga maritima. In three crystal forms the… CONTINUE READING
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