Crystal structures of human mitochondrial branched chain aminotransferase reaction intermediates: ketimine and pyridoxamine phosphate forms.

Abstract

The three-dimensional structures of the isoleucine ketimine and the pyridoxamine phosphate forms of human mitochondrial branched chain aminotransferase (hBCATm) have been determined crystallographically at 1.9 A resolution. The hBCATm-catalyzed transamination can be described in molecular terms together with the earlier solved pyridoxal phosphate forms of… (More)

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@article{Yennawar2002CrystalSO, title={Crystal structures of human mitochondrial branched chain aminotransferase reaction intermediates: ketimine and pyridoxamine phosphate forms.}, author={Neela H Yennawar and M. E. Conway and Hemant P. Yennawar and Gregory K. Farber and Susan M. Hutson}, journal={Biochemistry}, year={2002}, volume={41 39}, pages={11592-601} }