Crystal structures of NAC domains of human nascent polypeptide-associated complex (NAC) and its αNAC subunit

Abstract

Nascent polypeptide associated complex (NAC) and its two isolated subunits, αNAC and βNAC, play important roles in nascent peptide targeting. We determined a 1.9 Å resolution crystal structure of the interaction core of NAC heterodimer and a 2.4 Å resolution crystal structure of αNAC NAC domain homodimer. These structures provide detailed information of NAC… (More)
DOI: 10.1007/s13238-010-0049-3

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