Crystal structure of the sodium–potassium pump

@article{Morth2007CrystalSO,
  title={Crystal structure of the sodium–potassium pump},
  author={Jens Preben Morth and Bj{\o}rn Panyella Pedersen and Mads S. Toustrup-Jensen and Thomas Lykke-M{\o}ller S{\o}rensen and Janne Petersen and Jens Peter Andersen and Bente Vilsen and Poul Nissen},
  journal={Nature},
  year={2007},
  volume={450},
  pages={1043-1049}
}
The Na+,K+-ATPase generates electrochemical gradients for sodium and potassium that are vital to animal cells, exchanging three sodium ions for two potassium ions across the plasma membrane during each cycle of ATP hydrolysis. Here we present the X-ray crystal structure at 3.5 Å resolution of the pig renal Na+,K+-ATPase with two rubidium ions bound (as potassium congeners) in an occluded state in the transmembrane part of the α-subunit. Several of the residues forming the cavity for rubidium… Expand
Crystal structure of the sodium–potassium pump at 2.4 Å resolution
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