Crystal structure of the site-specific recombinase, XerD.

@article{Subramanya1997CrystalSO,
  title={Crystal structure of the site-specific recombinase, XerD.},
  author={Hosahalli S. Subramanya and Lidia K Arciszewska and Robert A. Baker and Louise E. Bird and David J Sherratt and Dale B. Wigley},
  journal={The EMBO journal},
  year={1997},
  volume={16 17},
  pages={5178-87}
}
The structure of the site-specific recombinase, XerD, that functions in circular chromosome separation, has been solved at 2.5 A resolution and reveals that the protein comprises two domains. The C-terminal domain contains two conserved sequence motifs that are located in similar positions in the structures of XerD, lambda and HP1 integrases. However, the extreme C-terminal regions of the three proteins, containing the active site tyrosine, are very different. In XerD, the arrangement of active… CONTINUE READING

From This Paper

Topics from this paper.
42 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 42 extracted citations

Similar Papers

Loading similar papers…