Crystal structure of the motor domain of a class-I myosin.

  title={Crystal structure of the motor domain of a class-I myosin.},
  author={Martin Kollmar and Ulrike D{\"u}rrwang and Werner Kliche and Dietmar J Manstein and F Jon Kull},
  journal={The EMBO journal},
  volume={21 11},
The crystal structure of the motor domain of Dictyostelium discoideum myosin-IE, a monomeric unconventional myosin, was determined. The crystallographic asymmetric unit contains four independently resolved molecules, highlighting regions that undergo large conformational changes. Differences are particularly pronounced in the actin binding region and the converter domain. The changes in position of the converter domain reflect movements both parallel to and perpendicular to the actin axis. The… CONTINUE READING

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