Crystal structure of the N-terminal domain of Nup358/RanBP2.

  title={Crystal structure of the N-terminal domain of Nup358/RanBP2.},
  author={Susanne A. Kassube and Tobias Stuwe and Daniel H. Lin and C Danielle Antonuk and Johanna Napetschnig and G{\"u}nter Blobel and Andr{\'e} Hoelz},
  journal={Journal of molecular biology},
  volume={423 5},
Key steps in mRNA export are the nuclear assembly of messenger ribonucleoprotein particles (mRNPs), the translocation of mRNPs through the nuclear pore complex (NPC), and the mRNP remodeling events at the cytoplasmic side of the NPC. Nup358/RanBP2 is a constituent of the cytoplasmic filaments of the NPC specific to higher eukaryotes and provides a multitude of binding sites for the nucleocytoplasmic transport machinery. Here, we present the crystal structure of the Nup358 N-terminal domain (NTD… CONTINUE READING
4 Citations
62 References
Similar Papers


Publications referenced by this paper.
Showing 1-10 of 62 references

Molecular basis for the anchoring of proto-oncoprotein nup98 to the cytoplasmic face of the nuclear pore complex

  • T. Stuwe, L. Schada von Borzyskowski, A. M. Davenport, A. Hoelz
  • J. Mol. Biol
  • 2012
2 Excerpts

Similar Papers

Loading similar papers…