Crystal structure of recombinant human interleukin-4.

@article{Walter1992CrystalSO,
  title={Crystal structure of recombinant human interleukin-4.},
  author={M. R. Walter and W. Cook and B. Zhao and R. Cameron and S. Ealick and R. Walter and P. Reichert and T. L. Nagabhushan and P. Trotta and C. Bugg},
  journal={The Journal of biological chemistry},
  year={1992},
  volume={267 28},
  pages={
          20371-6
        }
}
The crystal structure of recombinant human interleukin-4 (rhuIL-4) was initially determined at 3.5-A resolution by multiple isomorphous replacement techniques and subsequently refined to a resolution of 2.35 A by simulated annealing. The final crystallographic R-factor, based on all data in the range 6.0-2.35 A (7470 reflections), is 0.232. Bond lengths and bond angles in the molecule have root mean square deviations from ideal values of 0.016 A and 2.4 degrees, respectively. The overall… Expand
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