Crystal structure of recombinant human interleukin-4.

@article{Walter1992CrystalSO,
  title={Crystal structure of recombinant human interleukin-4.},
  author={Mark R. Walter and William Cook and B G Zhao and Rebecca P. Cameron and Steven E. Ealick and Richard L. Walter and P. G. Reichert and Tattanahalli L. Nagabhushan and Paul P. Trotta and Charles E. Bugg},
  journal={The Journal of biological chemistry},
  year={1992},
  volume={267 28},
  pages={
          20371-6
        }
}
  • Mark R. Walter, William Cook, +7 authors Charles E. Bugg
  • Published in
    The Journal of biological…
     1992
  • Chemistry, Medicine
    • The crystal structure of recombinant human interleukin-4 (rhuIL-4) was initially determined at 3.5-A resolution by multiple isomorphous replacement techniques and subsequently refined to a resolution of 2.35 A by simulated annealing. The final crystallographic R-factor, based on all data in the range 6.0-2.35 A (7470 reflections), is 0.232. Bond lengths and bond angles in the molecule have root mean square deviations from ideal values of 0.016 A and 2.4 degrees, respectively. The overall… CONTINUE READING
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