Crystal structure of photolysed carbonmonoxy-myoglobin

@article{Schlichting1994CrystalSO,
  title={Crystal structure of photolysed carbonmonoxy-myoglobin},
  author={Ilme Schlichting and Joel Berendzen and George N. Phillips and Robert M. Sweet},
  journal={Nature},
  year={1994},
  volume={371},
  pages={808-812}
}
MYOGLOBIN is a globular haem protein that reversibly binds lig-ands such as O2 and CO. Single photons of visible light can break the covalent bond between CO and the haem iron in carbonmonoxy-myoglobin (MbCO) and thus form an unstable intermediate, Mb*CO, with the CO inside the protein1,2. The ensuing rebinding process has been extensively studied as a model for the interplay of dynamics, structure and function in protein reactions. We have used X-ray crystallography at liquid-helium… CONTINUE READING