Crystal structure of Thermotoga maritima ribosome recycling factor: a tRNA mimic.

@article{Selmer1999CrystalSO,
  title={Crystal structure of Thermotoga maritima ribosome recycling factor: a tRNA mimic.},
  author={Maria Selmer and Salam Al-Karadaghi and Go Hirokawa and Akira Kaji and Anders Liljas},
  journal={Science},
  year={1999},
  volume={286 5448},
  pages={2349-52}
}
Ribosome recycling factor (RRF), together with elongation factor G (EF-G), catalyzes recycling of ribosomes after one round of protein synthesis. The crystal structure of RRF was determined at 2.55 angstrom resolution. The protein has an unusual fold where domain I is a long three-helix bundle and domain II is a three-layer beta/alpha/beta sandwich. The molecule superimposes almost perfectly with a transfer RNA (tRNA) except that the amino acid-binding 3' end is missing. The mimicry suggests… CONTINUE READING