Crystal structure of Escherichia coli MscS, a voltage-modulated and mechanosensitive channel.

Abstract

The mechanosensitive channel of small conductance (MscS) responds both to stretching of the cell membrane and to membrane depolarization. The crystal structure at 3.9 angstroms resolution demonstrates that Escherichia coli MscS folds as a membrane-spanning heptamer with a large cytoplasmic region. Each subunit contains three transmembrane helices (TM1, -2… (More)

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Cite this paper

@article{Bass2002CrystalSO, title={Crystal structure of Escherichia coli MscS, a voltage-modulated and mechanosensitive channel.}, author={Randal B Bass and Pavel Strop and Margaret Barclay and Douglas C Rees}, journal={Science}, year={2002}, volume={298 5598}, pages={1582-7} }