Crystal structure of Arabidopsis thaliana glutamyl-tRNAGlureductase in complex with NADPH and glutamyl-tRNAGlureductase binding protein

@article{Zhao2018CrystalSO,
  title={Crystal structure of Arabidopsis thaliana glutamyl-tRNAGlureductase in complex with NADPH and glutamyl-tRNAGlureductase binding protein},
  author={Aiguo Zhao and F. Han},
  journal={Photosynthesis Research},
  year={2018},
  volume={137},
  pages={443-452}
}
In higher plants, the tetrapyrrole biosynthesis pathway starts from the reaction catalyzed by the rate-limiting enzyme, glutamyl-tRNAGlu reductase (GTR). In Arabidopsis thaliana, GTR is controlled by post-transcriptional regulators such as GTR binding protein (GBP), which stimulates AtGTR activity. The NADPH-binding domain of AtGTR undergoes a substantial movement upon GBP binding. Here, we report the crystal structure of AtGTR-NADPH-GBP ternary complex. NADPH binding causes slight structural… Expand
2 Citations

References

SHOWING 1-10 OF 34 REFERENCES
Crystal structure of Arabidopsis glutamyl-tRNA reductase in complex with its stimulator protein
Escherichia coli Glutamyl-tRNA Reductase
...
1
2
3
4
...