Crystal size and properties of superparamagnetic iron oxide (SPIO) particles.

  title={Crystal size and properties of superparamagnetic iron oxide (SPIO) particles.},
  author={C E Sj{\"o}gren and Christian Johansson and A Naevestad and Per Christian Sontum and Karen Briley-Saeb\o and A K Fahlvik},
  journal={Magnetic resonance imaging},
  volume={15 1},
The properties of a superparamagnetic iron oxide (SPIO) model contrast agent have been studied. The test material, HEP-SPIO, contained iron oxide multicrystal agglomerates coated with heparin, polyanionic, naturally occurring glycosaminoglycan. Fractionation of the HEP-SPIO suspension showed the existence of colloidally stable particles ranging from approx. 100 nm down to single crystal sizes. The small (< 20 nm) particles represented the major number fraction of particles present, but only… CONTINUE READING
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