Crystal-induced arthropathies: recent investigative advances.

  title={Crystal-induced arthropathies: recent investigative advances.},
  author={Michael H Ellman and Michael Becker},
  journal={Current opinion in rheumatology},
  volume={18 3},
PURPOSE OF REVIEW To highlight recent investigations that have stimulated renewed interest in crystal-induced arthropathies. RECENT FINDINGS Specific diet-related and alcohol-related risks for gout have been clarified, and alternative urate-lowering treatments likely to benefit patients with difficult-to-treat gout are in development. Progress toward understanding mechanisms underlying the renal deficits defining most cases of gout includes characterization of a urate-specific renal tubule… CONTINUE READING