Crystal Structures of the uL3 Mutant Ribosome: Illustration of the Importance of Ribosomal Proteins for Translation Efficiency

Abstract

The ribosome has been described as a ribozyme in which ribosomal RNA is responsible for peptidyl-transferase reaction catalysis. The W255C mutation of the universally conserved ribosomal protein uL3 has diverse effects on ribosome function (e.g., increased affinities for transfer RNAs, decreased rates of peptidyl-transfer), and cells harboring this mutation… (More)
DOI: 10.1016/j.jmb.2016.02.013

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@inproceedings{Mailliot2016CrystalSO, title={Crystal Structures of the uL3 Mutant Ribosome: Illustration of the Importance of Ribosomal Proteins for Translation Efficiency}, author={Justine Mailliot and Nicolas Garreau de Loubresse and Gulnara Zh. Yusupova and Arturas Meskauskas and Jonathan D. Dinman and Gulnara Yusupova}, booktitle={Journal of molecular biology}, year={2016} }