Crystal Structure of the Ribosome at 5.5 Å Resolution

@article{Yusupov2001CrystalSO,
  title={Crystal Structure of the Ribosome at 5.5 {\AA} Resolution},
  author={Marat Yusupov and Gulnara Yusupova and A. Baucom and Kate R. Lieberman and Thomas N. Earnest and Jamie H. D. Cate and Harry F. Noller},
  journal={Science},
  year={2001},
  volume={292},
  pages={883 - 896}
}
We describe the crystal structure of the complete Thermus thermophilus 70S ribosome containing bound messenger RNA and transfer RNAs (tRNAs) at 5.5 angstrom resolution. All of the 16S, 23S, and 5S ribosomal RNA (rRNA) chains, the A-, P-, and E-site tRNAs, and most of the ribosomal proteins can be fitted to the electron density map. The core of the interface between the 30S small subunit and the 50S large subunit, where the tRNA substrates are bound, is dominated by RNA, with proteins located… 

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