Crystal Structure of the Eukaryotic 60S Ribosomal Subunit in Complex with Initiation Factor 6

@article{Klinge2011CrystalSO,
  title={Crystal Structure of the Eukaryotic 60S Ribosomal Subunit in Complex with Initiation Factor 6},
  author={S. Klinge and F. Voigts-Hoffmann and M. Leibundgut and S. Arpagaus and N. Ban},
  journal={Science},
  year={2011},
  volume={334},
  pages={941 - 948}
}
The 3.5 angstrom–resolution structure provides insights into the architecture of the eukaryotic ribosome and its regulation. Protein synthesis in all organisms is catalyzed by ribosomes. In comparison to their prokaryotic counterparts, eukaryotic ribosomes are considerably larger and are subject to more complex regulation. The large ribosomal subunit (60S) catalyzes peptide bond formation and contains the nascent polypeptide exit tunnel. We present the structure of the 60S ribosomal subunit… Expand
High-resolution structure of the eukaryotic 80S ribosome.
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  • G. Yusupova, M. Yusupov
  • Biology, Medicine
  • Philosophical Transactions of the Royal Society B: Biological Sciences
  • 2017
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Cryo-EM structure of the archaeal 50S ribosomal subunit in complex with initiation factor 6 and implications for ribosome evolution.
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References

SHOWING 1-10 OF 54 REFERENCES
Localization of eukaryote-specific ribosomal proteins in a 5.5-Å cryo-EM map of the 80S eukaryotic ribosome
Structure of the 30S ribosomal subunit
Crystal structures of ribosome anti-association factor IF6
Cryo-EM structure and rRNA model of a translating eukaryotic 80S ribosome at 5.5-Å resolution
...
1
2
3
4
5
...