Crystal Structure of the Aequorea victoria Green Fluorescent Protein

@article{Ormo1996CrystalSO,
  title={Crystal Structure of the Aequorea victoria Green Fluorescent Protein},
  author={M. Ormö and A. B. Cubitt and K. Kallio and L. Gross and R. Tsien and S. Remington},
  journal={Science},
  year={1996},
  volume={273},
  pages={1392 - 1395}
}
The green fluorescent protein (GFP) from the Pacific Northwest jellyfish Aequorea victoria has generated intense interest as a marker for gene expression and localization of gene products. The chromophore, resulting from the spontaneous cyclization and oxidation of the sequence -Ser65 (or Thr65)-Tyr66-Gly67-, requires the native protein fold for both formation and fluorescence emission. The structure of Thr65 GFP has been determined at 1.9 angstrom resolution. The protein fold consists of an 11… Expand
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