author={Rachel M. Chalmers and Angharad P Davies and Kevin Tyler},
  volume={165 5},
The protozoan Cryptosporidium is notorious for its resistance to chlorine disinfection, a mainstay of water treatment. Human infections, mainly of the small intestine, arise from consumption of faecally contaminated food or water, environmental exposure, and person-to-person or animal-to-person spread. Acute gastrointestinal symptoms can be prolonged but are usually self-limiting. Problems arise with immune-deficient, including malnourished, people including chronic diarrhoea, hepato-biliary… 

Molecular Epidemiology of Human Cryptosporidiosis in Low- and Middle-Income Countries

It is suggested that WASH (water, sanitation, and hygiene)-based interventions should be implemented to prevent and control human cryptosporidiosis in low- and middle-income countries.

Performance of Sewage Treatment Technologies for the Removal of Cryptosporidium Sp. And Giardia Sp.: Toward Water Circularity

The removal or inactivation efficiency of different treatment technologies presented by around 40 scientific studies was evaluated, with a view to water circularity, and it is concluded that the most efficient secondary technologies are aerobic technologies, with activated sludge presenting the greatest efficiency.

Global prevalence and risk factors of Cryptosporidium infection in Equus: A systematic review and meta-analysis

This metaanalysis systematically presented the global prevalence and potential risk factors of Cryptosporidium infection in Equus and advised the farmers to strengthen the management of young and female Equus animals, improve water filtration systems, reduce stocking densities, and harmless treatment of livestock manure.



Genetic modification of the diarrheal pathogen Cryptosporidium parvum

The ability to genetically engineer this parasite will be transformative for Cryptosporidium research and genetic reporters will provide quantitative correlates for disease, cure and protection, and the role of parasite genes in these processes is now open to rigorous investigation.

Continuous culture of Cryptosporidium parvum using hollow fiber technology.

Evolutionary genomics of anthroponosis in Cryptosporidium

It is shown that Cryptosporidium parvum splits into two subclades and that the specialist anthroponotic subtype IIc-a shares a subset of loci with C. hominis that is undergoing rapid convergent evolution driven by positive selection.

Cryptosporidium Infection Risk: Results of New Dose‐Response Modeling

Cryptosporidium human dose‐response data from seven species/isolates are used to investigate six models of varying complexity that estimate infection probability as a function of dose, suggesting additional inactivation and removal via treatment may be needed to meet any specified risk target.