Cryptococcus neoformans meningitis in the rat.


The primary clinical manifestation of Cryptococcus neoformans infection in humans is meningoencephalitis. To study the defense mechanisms that participate in the host response against C. neoformans infection of the central nervous system (CNS), we have developed a new model of cryptococcal meningitis in rats. Intracisternal inoculation of C. neoformans… (More)


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@article{Goldman1996CryptococcusNM, title={Cryptococcus neoformans meningitis in the rat.}, author={David L. Goldman and Arnau Casadevall and Y. Cho and S. C. Lee}, journal={Laboratory investigation; a journal of technical methods and pathology}, year={1996}, volume={75 6}, pages={759-70} }