Cryptococcus neoformans: gastronomic delight of a soil ameba.

  title={Cryptococcus neoformans: gastronomic delight of a soil ameba.},
  author={L A Bunting and J. B. Neilson and Glenn S. Bulmer},
  volume={17 3},
During 7 days of incubation in vitro the trophozoite stage of the free-living soil amoeba, Acanthamoeba polyphaga, phagocytized and killed 78-97% of the cells of three strains of Cryptococcus neoformans. With one strain, incubation time was increased to nine days and 99% of the yeast cells were killed. It was calculated that during 4-9 days of incubation a single trophozoite phagocytized and killed a daily average of 84 yeast cells. The lethal effect of A. polyphaga on C. neoformans may… CONTINUE READING

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