Cryptococcosis Serotypes Impact Outcome and Provide Evidence of Cryptococcus neoformans Speciation

  title={Cryptococcosis Serotypes Impact Outcome and Provide Evidence of Cryptococcus neoformans Speciation},
  author={Marie Desnos-Ollivier and Sweta Patel and Doroth{\'e}e Raoux-Barbot and Joseph Heitman and Françoise Dromer and J M Achard and Dominique Chabasse and J. Ph. Bouchara and S K Bland and Jean Pierre Bru and Marc Pulik and F. Leturdu and X. Lepeu and H{\'e}l{\`e}ne Lefrand and Charlotte Louise Jensen and Marion Ferrand and Manuel Larrouy and Michelle Bentata and Claire Bouges-Michel and Juliette Camuset and Lo{\"i}c Guillevin and Bernard Jarrousse and Mathilde Robineau and J. J. Rousset and Bernard Couprie and Michel Dupon and Herv{\'e} Dutronc and J. Y. Lacut and J. L. Pellegrin and J. M. Ragnaud and Jean François Viallard and F. X. Weill and Marie Elisabeth Bougnoux and X. Montreal and S. Morelon and Elisabeth Rouveix and Philippe Granier and Henri de Montclos and Allison Desveaux and M. Gavignet and A. S. Labussiere and Michel Mornet and Luc de Saint-Martin and Elodie Moalic and Jacques Roucoul{\`e}s and J. F. Loriferne and G. Otterbein and J. F. Desson and Michel Leporrier and Chantal Duhamel and Julie Bonhomme and J. M. Korach and Beatriz Cristina Silveira Salles and Christelle Sir{\'e} and Vincent Herv{\'e} and Bertrand Souleau and Jean Beytout and Monique Cambon and Denis Pons and Philippe Poirier and Yves Boussougant and Didier Dreyfuss and X. Michon and Philippe Vinceneux and G. Belkacem-Belkaki and St{\'e}phane Bretagne and Michel Chousterman and P. Grimberg and Anne Sophie Lascaux and Anke Schaeffer and Alain Sobel and J. L. Bacri and Gilles Berthelot and Alain Bonnin and Michel Duong and Janice Lopez and Henri Portier and Fr{\'e}d{\'e}ric Dalle and Marie G Gauthier and Olivier Salmon and Jorge Bizet and J. L. Gaillard and Christian Perronne and M. A. Desailly and Herv{\'e} Maisonneuve and Jean Pierre P. B{\'e}dos and Julia Doll and Odile Eloy and Jean Claude Ghnassia and Sylvie Roussin-Bretagne and C{\'e}cile B Brocard and P. Guiffault and Antoine Layet and A. Morel and Françoise Botterel and Patrice Bour{\'e}e and Jean François Delfraissy and Y. Kertaimont and Ad{\'e}la Angoulvant and Pierre Lozeron and K. R{\'e}rat and G{\'e}rard Sa{\"i}d and X. Cricks and Marie Laure Dard{\'e} and Arnaud Jaccard and Bernard Bouteille and D. Azjenberg and Damien Bouhour and Eric Dannaoui and X. Mallet and Dominique Peyramond and M. A. Piens and Christian Tr{\'e}po and Laura Berardi and François Tr{\'e}moli{\`e}res and Yvon F. Berland and A. Blancard and Louis Collet and Jean P Delmont and Herv{\'e} Gallais and X. Gamby and Angeline M. Nguyen and J{\'e}r{\^o}me Moreau and Nathalie Petit and J. M. Sainty and J. Sampol-Roubicek and M. Bietrix and Meyer Nezri and Alain Fiacre and Shawn Levy and C. Chandesris and X. La Torre and Patricia O Andres and Eric Billaud and F. Boiffin and Mohamed Amine Hamidou and Odile Morin and Bernard Planchon and François Raffi and Daniel Villers and Florent Morio and Philippe Albert Clevenbergh and Francine de Salvador and Pierre Dellamonica and Xavier Durand and Martine Gari-Toussaint and Anette Romaru and Mich{\`e}le Texereau and Laurent Bret and T. Prazuk and Didier Marc Poisson and Xavier Bernard and Yves Pach{\'e}co and B Becq-giraudon and Catherine Kauffmann-Lacroix and Jean Claude Meurice and Thierry Pasdeloup and Jaime Deville and Dominique Toubas and C{\'e}dric Arvieux and Flora Cartier and Sylviane Chevrier and Brigitte Degeilh and Thierry Frouget and Claude Guiguen and P. Le Cavorzin and J. P. Gangneux and Christian Michelet and Val{\'e}rie Noyon and Philippe Abboud and Philippe Brasseur and Jo{\"e}l Leroy and Jean François Muir and Lo{\"i}c Favennec and P. Babinet and François Fraisse and Nadine Godineau and Samia Hamane and P. Margent and Denis Mechali and Marie Thuong and Charles Pierre Soler and B. Hery and J. Y. Leberre and A Gregory and O. Prevot and Daniel Christmann and Jessica L. Waller and Val{\'e}rie Letscher-Bru and Olivier Bl{\'e}try and Pierre Cahen and David Zucman and Bernard Fortier and Xavier L. Aubert and St{\'e}phane Chadapaud and X. Delbeck and Alain Lafeuillade and X. Raoult and E Bonnet and Sophie Cassaing and Anne Gadroy and Marie Denise Linas and Jean François Magnaval and Patrice Massip and Laurent Prudhomme and Laurent J Sailler and V{\'e}ronique Baclet and Catherine Coignard and Yves Mouton and Isabelle Ravaux and Carmen Eloy and Arnaud Le Fur and L. Rezzouk and Clotilde Fontier and E. Mazards and M. F. Biava and Petra Canton and L. Kures and Christian 4 Rabaud and Marie Machouart and D. Vittecocq and Elisabeth Chachaty and Sophie Dellion and Olivier Patey and Olivier Benveniste and Christine M. Bouchard and Sandrine Belaich and Claus-Christian Carbon and Christian Chochillon and Jean P Coulaud and Vincent Descamps and Xavier Duval and Catherine Leport and F. Lheriteau and Pascale Longuet and Houria Mouas and F. Vachon and J. L. Vilde and Patrick G Yeni and V. Lavarde and Christophe Piketty and Boyan Christoforov and Jean Dupouy-Camet and J. P. Luton and A. Paugam and M. T. Baixench and Nicole Desplaces and Gilles Raguin and Patrick Chevalier and Michel O Kazatchkine and Alain Y Meyrier and Abel Bernadou and Murielle Cornet and J. P. Marie and S. Oudart and Martine Gayraud and Yves P{\'e}an and Christine Aznar and Bertrand Dupont and Hubert Poncelet and Amaury de Gouvelho and Clarisse Loyer and Odile Launay and Patrick Berche and V{\'e}ronique Math{\'e} and Laurence Baril and Philippe Bossi and François Bricaire and Jennifer Carri{\`e}re and Annick Datry and Serge Herson and Marc Jouan and Mich{\`e}le L{\'e}vy-Soussan and Claire Mouquet and B. Orcel and M. M. Thiebaut and J. Frottier and Jean-Baptiste Guiard-Schmidt and Bernadette Lebeau and Jean Luc Meynard and M. C. Meyohas and Jean Louis Poirot and Patricia Roux and X. Urban and Fariba Daniel and Jacques M. Gilquin and Julie F Timsit and Claire Lacroix and JC Brouet and J. M. Decazes and Francis Derouin and B. Eurin and J. R. Legall and C. Legendre and S{\'e}gol{\`e}ne Neuville and J. P. Escande and G. Delzant and Guillaume Kac and Christophe Trivalle and Anne Boulli{\'e} and Karine Boukris-Sitbon and Olivier Lortholary and Dea Garc{\'i}a-Hermoso and Damien Hoinard},
UNLABELLED Cryptococcus neoformans is a human opportunistic fungal pathogen causing severe disseminated meningoencephalitis, mostly in patients with cellular immune defects. This species is divided into three serotypes: A, D, and the AD hybrid. Our objectives were to compare population structures of serotype A and D clinical isolates and to assess whether… CONTINUE READING