Cryptococcal Phospholipase B1 Is Required for Intracellular Proliferation and Control of Titan Cell Morphology during Macrophage Infection

@inproceedings{Evans2015CryptococcalPB,
  title={Cryptococcal Phospholipase B1 Is Required for Intracellular Proliferation and Control of Titan Cell Morphology during Macrophage Infection},
  author={Robert Evans and Zhongming Li and William S. Hughes and Julianne Teresa Djordjevic and Kirsten Nielsen and Robin C May},
  booktitle={Infection and immunity},
  year={2015}
}
Cryptococcus neoformans is an opportunistic fungal pathogen and a leading cause of fungal-infection-related fatalities, especially in immunocompromised hosts. Several virulence factors are known to play a major role in the pathogenesis of cryptococcal infections, including the enzyme phospholipase B1 (Plb1). Compared to other well-studied Cryptococcus neoformans virulence factors such as the polysaccharide capsule and melanin production, very little is known about the contribution of Plb1 to… CONTINUE READING
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