Corpus ID: 80822492

Cryptic Chromosome Abormalities in Acute Leukaemia: Identification and Detection

@inproceedings{Zutven2005CrypticCA,
  title={Cryptic Chromosome Abormalities in Acute Leukaemia: Identification and Detection},
  author={L.J.C.M. van Zutven},
  year={2005}
}
  • L.J.C.M. van Zutven
  • Published 2005
  • Biology
  • textabstractSpecific chromosome aberrations are observed in 50% of all new acute leukaemia patients. As a result of chromosome aberrations, genes located at the breakpoints can be disrupted and fusion genes can be formed. In addition, genes can be lost or amplified. An increasing number of these rearrangements are specific and can be correlated with diagnosis, prognosis and response to therapy. In the other 50% of new leukaemia patients no or non-specific abnormalities are found. It is thought… CONTINUE READING
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