Cryopreserved deglycerolized blood is safe and achieves superior tissue oxygenation compared with refrigerated red blood cells: A prospective randomized pilot study

@article{Fabricant2013CryopreservedDB,
  title={Cryopreserved deglycerolized blood is safe and achieves superior tissue oxygenation compared with refrigerated red blood cells: A prospective randomized pilot study},
  author={Loic J. Fabricant and Laszlo N. Kiraly and C. Wiles and J. Differding and S. Underwood and T. Deloughery and M. Schreiber},
  journal={Journal of Trauma and Acute Care Surgery},
  year={2013},
  volume={74},
  pages={371–377}
}
BACKGROUND During preservation, donated liquid red blood cells (RBCs) experience multiple functional and structural changes known as the storage lesion. Increased RBC age is associated with increased infection rates, organ failure, and mortality. METHODS This prospective, randomized, double-blinded pilot study enrolled stable trauma patients who required RBC transfusion. Patients were randomly assigned to receive standard or cryopreserved RBCs. Continuous tissue oxygenation (StO2) monitoring… Expand

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