Cryopreserved deglycerolized blood is safe and achieves superior tissue oxygenation compared with refrigerated red blood cells: a prospective randomized pilot study.

@article{Fabricant2013CryopreservedDB,
  title={Cryopreserved deglycerolized blood is safe and achieves superior tissue oxygenation compared with refrigerated red blood cells: a prospective randomized pilot study.},
  author={Loic J Fabricant and Laszlo Dipl Chem Kiraly and Connor L Wiles and Jerome A. Differding and Samantha A Underwood and Thomas Deloughery and Martin A. Schreiber},
  journal={The journal of trauma and acute care surgery},
  year={2013},
  volume={74 2},
  pages={
          371-6; discussion 376-7
        }
}
BACKGROUND During preservation, donated liquid red blood cells (RBCs) experience multiple functional and structural changes known as the storage lesion. Increased RBC age is associated with increased infection rates, organ failure, and mortality. METHODS This prospective, randomized, double-blinded pilot study enrolled stable trauma patients who required RBC transfusion. Patients were randomly assigned to receive standard or cryopreserved RBCs. Continuous tissue oxygenation (StO2) monitoring… CONTINUE READING

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Cryopreserved red blood cells are superior to standard liquid red blood cells.

  • The journal of trauma and acute care surgery
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