Cryopreservation of rat pancreatic islets: effect of ethylene glycol on islet function and cellular composition.


BACKGROUND Inasmuch as cryopreservation can facilitate clinical islet transplantation by providing a means of storing supplemental islets in order to augment marginally adequate grafts, protocols are needed to allow for a minimal loss in viable beta cells. By replacing the cryoprotectant dimethyl sulfoxide (DMSO) with ethylene glycol (EG), a more simplified… (More)


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