Cryopreservation of human spermatozoa with pentoxifylline improves the post-thaw agonist-induced acrosome reaction rate.

@article{Esteves1998CryopreservationOH,
  title={Cryopreservation of human spermatozoa with pentoxifylline improves the post-thaw agonist-induced acrosome reaction rate.},
  author={Sandro C. Esteves and Ranjna Sharma and Anthony Joseph Thomas and Anupam Agarwal},
  journal={Human reproduction},
  year={1998},
  volume={13 12},
  pages={3384-9}
}
Cryopreservation causes extensive damage to spermatozoa, thereby impairing their fertilizing ability. The purpose of this study was to determine if the direct addition of pentoxifylline to the seminal plasma before cryopreservation improved sperm motility and acrosome reaction. Semen specimens from 15 healthy volunteers were divided into two aliquots. One aliquot was treated by adding 5 mM pentoxifylline directly to the seminal plasma (treatment group) and the other aliquot received no… CONTINUE READING