Cryopreservation of human monocytes for pharmacopeial monocyte activation test.

@article{Koryakina2014CryopreservationOH,
  title={Cryopreservation of human monocytes for pharmacopeial monocyte activation test.},
  author={A. S. Koryakina and Esther Frey and Peter Br{\"u}gger},
  journal={Journal of immunological methods},
  year={2014},
  volume={405},
  pages={
          181-91
        }
}
EU Directive 2010/63/EU regarding the protection of experimental animals came into force in November 2010 with an obligation for EU member states to incorporate its requirements into their respective national legislations by 1st of January 2013. The directive stipulates the application of in vitro methods to replace animal experiments whenever such an in vitro method exits and is recognized by EU legislation. The monocyte activation test (MAT) for the detection and quantification of pyrogenic… CONTINUE READING
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