Cryopreservation of follicles in human ovarian cortical tissue. Comparison of serum and human serum albumin in the cryoprotectant solutions.

@article{Hreinsson2003CryopreservationOF,
  title={Cryopreservation of follicles in human ovarian cortical tissue. Comparison of serum and human serum albumin in the cryoprotectant solutions.},
  author={Julius Gisli Hreinsson and Pu Zhang and Marja Liisa Swahn and Kjell R Hultenby and Outi Hovatta},
  journal={Human reproduction},
  year={2003},
  volume={18 11},
  pages={2420-8}
}
BACKGROUND Cryopreservation of follicles in ovarian cortical tissue has been suggested as a method for preserving fertility for young women who need to undergo cytotoxic therapy. Varying compositions of cryoprotectant solutions have been used to prevent tissue damage during cryopreservation and thawing. We compared human serum [20% (v/v)] and human serum albumin (HSA) (25 mg/ml) in cryoprotectant solutions containing propanediol and sucrose to evaluate whether serum-free medium could be used… CONTINUE READING

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