Cryopreservation Prevents Arterial Allograft Dilation

@article{Giglia2002CryopreservationPA,
  title={Cryopreservation Prevents Arterial Allograft Dilation 
},
  author={J. Giglia and J. Ollerenshaw and P. Dawson and K. Black and W. Abbott},
  journal={Annals of Vascular Surgery},
  year={2002},
  volume={16},
  pages={762-767}
}
Historically, immune-mediated degradation and subsequent aneurysm formation have limited the usefulness of cryopreserved arterial allografts. This study tested the hypothesis that modern cryopreserved arterial allografts are protected from immune-mediated dilation. Abdominal aortas were harvested from anesthetized rats (Lewis and Brown-Norway) for immediate implantation or cryopreservation. Subsequently, Lewis rats underwent infrarenal aortic replacement with either an acutely harvested or a… Expand
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