Cryoprecipitate transfusion: current perspectives

@article{Wong2016CryoprecipitateTC,
  title={Cryoprecipitate transfusion: current perspectives},
  author={Henna S Wong and Nicola S Curry},
  journal={International Journal of Clinical Transfusion Medicine},
  year={2016},
  volume={4},
  pages={89-97}
}
  • H. WongN. Curry
  • Published 22 September 2016
  • Medicine
  • International Journal of Clinical Transfusion Medicine
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References

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Cryoprecipitate therapy

Randomized, controlled trials are needed to determine the clinical efficacy of cryoprecipitate, compared with the efficacy of alternative preparations, to allow the development of evidence-based guidelines in order to inform physicians and guide clinical practice.

Cryoprecipitate: the current state of knowledge.

Early cryoprecipitate for trauma patients is feasible, but will it improve outcome?

’Fly’: overcoming the barriers to preoperative haemoglobin optimization in surgical patients is overcome and very-short-term perioperative intravenous iron administration and postoperative outcome in major orthopedic surgery is analyzed.

Guidelines for the use of fresh‐frozen plasma, cryoprecipitate and cryosupernatant

Fresh‐frozen plasma (FFP), cryoprecipitate and cryosupernatant plasma are very limited and should not be used to reverse warfarin anticoagulation in the absence of severe bleeding, and PRP may be used as an alternative to FFP.

Pharmacokinetic study of minipooled solvent/detergent‐filtered cryoprecipitate factor VIII

The data show that S/D‐F cryoprecipitate FVIII presents a normal pharmacokinetics profile, and support that it could be safely used for the control of acute and chronic bleeding episodes in haemophilia A patients.

Cryoprecipitate versus commercial fibrinogen concentrate in patients who occasionally require a therapeutic supply of fibrinogen: risk comparison in the case of an emerging transfusion-transmitted infection.

A probabilistic model was used to compare cryoprecipitate to viral inactivated, commercial fibrinogen concentrate to evaluate with regard to the recipient's risk of exposure to an emergent AIDS-like

Hemostatic effects of fibrinogen concentrate compared with cryoprecipitate in children after cardiac surgery: a randomized pilot trial.

A critical evaluation of cryoprecipitate for replacement of fibrinogen

Wider availability and use of fibrinogen concentrate may improve the management of perioperative bleeding and further benefits may accrue from more rapid and accurate techniques for monitoring fibr inogen levels.

Thrombin generation and procoagulant microparticle profiles after acute trauma: A prospective cohort study

Although there was no predictable pattern of coagulopathy observed in each patient after trauma, those who reached extreme values did so relatively early after injury, and these findings should be taken into account when designing risk model tools involving coagulation laboratory parameters.

Early cryoprecipitate for major haemorrhage in trauma: a randomised controlled feasibility trial.

Early Fg supplementation using cryoprecipitate is feasible in trauma patients and supports the need for a definitive RCT to determine the effect of early Fg supplements on mortality and other clinical outcomes.
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